Senior Software Engineer (Platform Engineering)-Remote, USA

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Senior Software Engineer (Platform Engineering)-Remote, USA Purpose: The Senior Software Engineer is a hands-on technical leader responsible for architecting and delivering the Java-based services at the core of Ambry's platform modernization. This role ensures technology execution stays aligned with strategic business goals, owning the design and build of Spring Boot microservices that replace legacy monolith functionality. The position drives legacy system refactoring, cloud migration, microservices adoption, and CI/CD maturity across the engineering organization. It safeguards architectural coherence, actively mitigates technical debt, and provides the senior technical judgment needed to keep major initiatives on schedule and operationally sound. Essential Functions: Own the end-to-end architecture, design, and implementation of Java and Spring Boot microservices across the platform. Define and evangelize target-state architecture, service boundaries, and upgrade paths, and document them for engineering and stakeholder audiences. Lead the decomposition of legacy PHP/Symfony monolith functionality into resilient, independently deployable Java services. Design and build AWS-native solutions using ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, and Parameter Store. Build and maintain secure REST APIs with robust validation, error handling, authentication, and authorization. Drive identity modernization, including OAuth2/OIDC and the LDAP-to-Okta migration. Design and optimize data access layers using JPA/Hibernate, including ORM mappings, schema evolution, index strategy, and query tuning. Establish engineering standards for unit and integration testing, CI/CD pipelines, observability, logging, and alerting. Partner with QA, DevOps, Product, Architecture, and Regulatory teams to deliver compliant, production-ready software. Mentor engineers across levels through code review, design review, and knowledge sharing. Lead technical planning and execution of complex, multi-sprint initiatives, and surface delivery risk early. Troubleshoot and resolve production issues affecting service performance, stability, and reliability. Maintain awareness of and compliance with SOX and HIPAA requirements in a regulated healthcare environment. Other duties as assigned. Qualifications: 10+ years of professional software engineering experience with a strong backend focus. Expert-level proficiency in Java and Spring Boot, with deep experience in distributed systems. Demonstrated experience decomposing monolithic applications into microservices. Hands-on experience with AWS services (ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, IAM). Strong command of REST API design, authentication and authorization patterns, and enterprise integration. Strong experience with relational databases (MySQL/Aurora) and ORM frameworks such as Hibernate/JPA, including query tuning. Proficiency with Docker, CI/CD pipelines, and cloud-native delivery practices. Proven ability to lead technical direction and mentor engineers across levels. Bachelor's degree in Computer Science, Software Engineering, or equivalent experience. Excellent communication, problem-solving, and architectural decision-making skills. Preferred: Master's degree in Computer Science or a related field. Experience in healthcare, genomics, diagnostics, or other regulated environments. Experience with Okta or comparable identity providers. Working knowledge of PHP/Symfony sufficient to refactor legacy functionality. Experience with Kubernetes, Terraform, or comparable infrastructure-as-code tooling. Familiarity with Scaled Agile Framework (SAFe) practices. $130,000-$150,000 USD Annually The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster. At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program. The Company reserves the right to make changes to the 401k plan from time to time. You can learn more about the benefits here. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment. The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. For the purpose of the above job description, “Essential Functions” are “Material Job Duties”. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at careers@ambrygen.com Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly. To review Ambry’s Privacy Notice, click here: Ambry’s Privacy Notice To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics